things to know about semaglutide Ozempic vs. Wegovy vs. Mounjaro: What's the Difference? What to know about semaglutide

Clinical trials of semaglutide, including the SUSTAIN and STEP programs, have not demonstrated increased incidence of thyroid cancer compared to placebo or active comparators

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"States have the option, but are not required, to cover weight loss medication," a Centers for Medicare & Medicaid Services spokesperson said in an email to ABC News

GLP-1 receptor agonists like semaglutide stimulate insulin secretion, inhibit glucagon (a hormone that raises blood sugar), and slow gastric emptying

A bipartisan coalition of 38 state Attorneys General have called on the FDA to take swift action against compounding pharmacies that "cut corners in pursuit of a quick profit" and sell knockoff drugs that could lead to "serious public health issues." The Ohio Attorney General recently issued a press release about letters it sent to 14 entities warning them to stop deceiving patients into believing that compounded drugs are approved by the FDA or have been reviewed for safety, effectiveness, or quality and declaring that patients "deserve clear and accurate information about the medication they're putting in their bodies." Similarly, in December 2024, the Illinois Attorney General issued cease-and-desist letters to five Chicagoland med spas advertising name brand medications like Wegovy and Ozempic but "instead offering unapproved versions of these products that may put people's health at risk." In addition, over a dozen Attorneys General have issued statements discussing the dangers posed by knockoff "semaglutide," including North Carolina, South Carolina, and Tennessee

Both weight loss drugs contain semaglutide, miming the GLP-1 hormone that regulates appetite and insulin secretion