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If that occurred, then -glutamyl cysteine, the final substrate of the glutathione synthase reaction (Figure 2, reaction 5), would be shunted into the dotted line pathway shown in Figure 2 instead of synthesis of glutathione

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found that 52 weeks of once-weekly semaglutide (the active ingredient in Ozempic and Wegovy) reduced hip bone mineral density by 2.6% and lumbar spine density by 2.1% compared to placebo in adults with increased fracture risk

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