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2.5 Gastrointestinal Side Effects Common adverse effects during dose escalation include: Nausea Vomiting Diarrhoea Early satiety Persistent gastrointestinal symptoms may increase the risk of: Reduced caloric intake Reduced protein intake Electrolyte imbalance Dehydration Most symptoms improve with gradual titration and adaptation

Always use a new, sterile syringe for each injection

They can support weight reduction, cardiovascular health, and even renal protection, making them a powerful tool for patients managing several conditions

Baseline IGF-1 levels, body composition parameters, and growth hormone secretory status may serve as predictive biomarkers, though systematic validation is lacking

10.1016/j.ijpharm.2020.119500 237 ZhangX.WuC