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employed network pharmacology to identify the mechanism(s) and pathways underlying reduced myocardial infarction rates in DM patients receiving GLP-1 agonists

167 Furthermore, mice and humans differ substantially in insulin kinetics and blood glucose control

Broad interest is now focused on the biguanide metformin 37, 38 (see review in the same issue of this topical issue) as well as IR and IGF-1R inhibitors