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HER2 positive tumors, which comprise ~ 15% of all breast cancers, express high levels of HER2 but lack ER, and PR expression [3,4,5]
Glutathione is produced naturally by the body
Despite these inconsistencies, the safety profile of hydrogen therapy appears robust, with no major adverse effects reported in clinical trials
Officials proposed more than a dozen solutions, including several aimed at widening the drugs safety margin, such as lowering the maximum recommended daily dose and reducing the amount of the drug in each pill
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Our observations suggest that prior ICI exposure may lower the threshold for immune tolerance, thereby amplifying drug-induced immune responses
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