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GLP-1 receptor agonists like semaglutide (Ozempic, Wegovy) and the dual GLP-1/GIP agonist tirzepatide (Mounjaro) have delivered significant advances in weight management and blood sugar control

Many community references include 2-4 week off-periods between cycles to allow fresh evaluation, although the rationale is community-derived rather than trial-validated

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The common side effects are nausea, reflux, diarrhoea, constipation, reduced appetite, and fatigue

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