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A prespecified analysis of pooled data from the STEP-HFpEF and STEP-HFpEF DM trials demonstrated that significantly more patients treated with Wegovy 2.4 mg SC once weekly had an improvement of at least one in New York Heart Association (NYHA) functional class compared to those who received placebo (32.6% versus 21.5%, respectively

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Other factors that may increase infection risk in diabetes patients include: Immunosuppressive effects of poorly controlled hyperglycemia Neuropathy leading to reduced sensation and delayed recognition of infections Vascular complications impairing tissue perfusion and immune cell delivery Frequent antibiotic use for other infections, disrupting normal flora Obesity , which is common in type 2 diabetes and creates skin folds prone to moisture and fungal growth Conversely, medications that improve glycemic control, including GLP-1 receptor agonists and tirzepatide, generally reduce infection risk by normalizing the metabolic environment