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Researchers believe metabolic dysfunction, inflammation, and insulin resistance may contribute to neurodegeneration

This dual-action mechanism can lead to increased energy expenditure

However, in line with the existing classification of beriberi affecting nerves (dry beriberi) and cardiovascular system (wet beriberi), it is plausible to use the term gastrointestinal beriberi in an analogous, tissue-directed, way

Myxoid Degeneration: The replacement of smooth tissue with a jelly-like substance characterized by transparent connective tissue with a mucus-like appearance

PLoS Med 2005

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