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For the NAC rescue experiment, mice received intraperitoneal administration of 200 mg/kg of body weight NAC (A105422, Aladdin) in phosphate-buffered saline (pH 7.4) every second day for two weeks

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From a public health standpoint, the impact of TMAO elevation during l-carnitine supplementation is unknown, but both vegan/vegetarian and omnivore on average showed a greater than 10-M increase in circulating TMAO levels with l-carnitine supplementation

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