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The reasoning is that a partially full stomach may buffer some of the initial GI effects

Constipation treatment approaches are similar across the class

That last part is key: slowed gastric emptying is part of how these medications make you feel fuller longer

Only the albumin variants with an isoleucine (L585I), a methionine (L585M), or a valine (L585V) showed binding curves similar to that obtained for the WT albumin (Fig