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In condizioni di iperglicemia e glicogeno elevato, aumenta il malonil-CoA , che inibisce CPT1 e riduce l'ingresso degli acidi grassi nei mitocondri (favorendo la sintesi lipidica)

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GLP-1 receptor agonists are cleared via renal pathways, and their use in patients with moderate-to-severe chronic kidney disease (CKD) requires careful consideration

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