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It is triggered by activation of inflammatory caspases, such as caspase-1, via inflammasomes (e.g., NLRP3), leading to the release of pro-inflammatory cytokines IL-1 and IL-18 and resulting in membrane rupture

For example, crude protein over-supplementation may impair embryo development, necessitating guidelines to avoid unintended harm ( 6 Conclusion Dietary supplements and nutritional interventions influence oocyte quality through diverse mechanisms across species, targeting oxidative stress, mitochondrial function, and metabolic pathways

The Leyden 2002 and Abdulghani 1998 studies are smaller and older 13 14