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Side effects, if they occur, are usually mild and may include facial flushing, skin rash, redness or tenderness at the injection site, dizziness, nausea, and headache

Mojca Jensterle Sever of the University of Ljubljana, is that obesity is still perceived as a lifestyle disease. But because obesity is a disease that requires clinical intervention to provide meaningful benefits, medications should be considered in certain individuals

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[DOI] [Google Scholar] 30.Zerarka-Chabane N., Laraba-Djebari F., Hammoudi-Triki D

Patients with GI sensitivity: While orforglipron's GI side effect profile is broadly similar to injectable GLP-1s, the daily oral dosing means the GI tract is exposed to the active compound on a different kinetic schedule than weekly injections