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10.1016/j.jmb.2007.09.041 21 CsiszarJ.HorvathE.VaryZ.GalleA.BelaK.BrunnerS.et al
After first use: Most formulations remain stable for 28 days after first puncture when stored properly
One of the lesser oxidative metabolites, 4-ene-VPA, causes hepatotoxicity in rats
Moreover, mRNA studies also demonstrate the presence of this receptor in limbic and mesolimbic structures known to be involved in motor control, emotional reactivity and reward/motivation systems such as the hippocampus (dentate gyrus, CA2, and CA3 regions), pars compacta of the substantia nigra, ventral tegmental area (VTA), raphe nuclei, laterodorsal tegmental nucleus (Guan et al., 1997
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