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Badr BM, Moustafa NA, Eldien HM, Mohamed AO, Ibrahim HM, El-Alaimy IA, Mahmoud MH, Badr G

Abstract Background: Tirzepatide, a dual glucose-dependent insulinotropic polypeptide, (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, has emerged as an effective therapy for obesity and type 2 diabetes mellitus (T2DM)

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The reason for slow escalation is straightforward: gastrointestinal side effects like nausea, vomiting, and constipation are dose-dependent

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