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Given its essential role in the detoxification of lipid hydroperoxides, and its overexpression in most of myeloid malignancies, GPX4 inhibition has emerged as a promising therapeutic strategy to specifically trigger ferroptosis and eradicate myeloid leukemia cells

These may indicate acute kidney injury or electrolyte imbalance

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The most common side effects of this medicine include nausea, vomiting, headache, and injection site reactions

Biochimica et Biophysica Acta (BBA) - Biomembranes