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However, in a depleted state, these defenses fail

Materials and methods Animals and the induction of ARF The Institutional Animal Care & Ethics Committee of the Faculty of Veterinary Medicine at Assiut University granted consent to this experiment (approval number: 06/2024/0187), and all ARRIVE regulations were followed

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doi: 10.3389/fphar.2025.1654372 Received 26 June 2025 Accepted 05 August 2025 Published 18 August 2025 Volume 16 - 2025 Edited by Abbas Choudhury, VIT University, India Reviewed by Evelyn Weaver, The Pennsylvania State University (PSU), United States Marcelo Adrian Estrin, Interamerican Open University, Argentina Updates Copyright 2025 Zeng, Luo, Ou, Gan, Huang, Tomlinson and Jiang

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There is one accepted guideline: People who are more physically active might benefit from a higher dosage, compared to a less active person whos taking glutamine for their general health