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Together, characterization and application of the ataxin-2-specific proteases demonstrate that evolution from redesigned proteases yielded solutions to the dual-selection challenge with higher expression, activity and specificity for a non-native target of therapeutic interest than evolution from WT enzymes

Molecular simulations confirmed CAGs binding to the hTERT model, and its subsequent application rejuvenated telomerase activity, restoring ovarian health in age-induced and Doxorubicin-induced damage models

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Glutathione treatments should always be conducted under the supervision of a medical professional

It seems plausible that gene regions with low/moderate CG frequency might be more prone to experience dynamic changes in their methylation, however, whether this is a consequence of their dynamic transcription remains elusive