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16 weeks of dosing were used with up-titration every second week to reach different maintenance doses of twelve (2.4 mg), eight (4.8 mg) and six (9.0 mg) weeks, respectively

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A clear demonstration was obtained that BPC 157 stimulated both the egr-1 gene (critical in proliferation, differentiation, and inflammation during cholestatic liver injury, cytokine and growth factor generation, and early extracellular matrix (collagen) formation) (Kim et al., 2006

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