moa glp 1 Mechanism of action of GLP-1 [25] Type 2 Diabetes Treatment Novel

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GLP-1R signaling enhances glucose-dependent insulin secretion by activating of G s , upregulating of cAMP, and subsequently activating of PKA (110)

Ashraf A, Jeandriens J, Parkes HG, So PW

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This effect is shared with other GHRPs and contributes to the synergistic GH release observed when GHRPs are combined with GHRH analogs