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For example: In the SURMOUNT-1 trial, participants taking tirzepatide lost up to 22.5% of body weight over 72 weeks

1,55 Chronic treatment with exenatide induced cell proliferation in the rat dentate gyrus of the hippocampus with elevated Ki-67 gene expression (a cellular marker of proliferation used to determine the growth fraction of a cell population, as it is present during all active phases of the cell cycle [G 1 , S, G 2 , and mitosis] but is absent from resting cells [G 0 ])

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