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Groups at higher risk include older adults, people with kidney disease, people with autoimmune conditions, heavy alcohol consumers, and people taking certain medications that deplete B6 stores (including some oral contraceptives and isoniazid)

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HGF influenced the metastasis of c-MET-positive cells into multiple organs, including the liver, kidney, lymph nodes, lung, gonads, and the central nervous system, in SCID mice but did not affect metastasis of c-MET-negative lymphoma [15]