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This expression was evident in ARC, PVN, periaqueductal gray (PAG), AP (area postrema), LPB, and IML of spinal cords, but not in the hippocampus, cortex, basal ganglia, suggesting that GLP-1RAs may be activating the CNS via multiple neuroendocrine pathways

It is important to note that in these studies, specific isoforms are often not reported, or they are reported to include classic PRKCA and PRKCE, possibly due to their availability in non-neuronal cell lines (platelets) (Wang et al., 1999)

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epidermidis compound responsible for GLP-1 stimulatory activity To identify the bacterial component responsible for GLP-1 secretion in vitro and for metabolic disease marker modulation in vivo , we performed size fractionation studies on conditioned supernatants of S