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A November 2025 study found that GLP-1 receptor antagonist (RA) use, including semaglutide, was associated with reduced rates of urinary retention and urinary tract infections (UTIs) in non-diabetic women receiving treatment for overactive bladder syndrome

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Data Animal Data In studies evaluating reproduction and development in pregnant mice and rabbits, maternal animals were administered exenatide, the active ingredient in BYETTA, by subcutaneous injection twice a day