Response: With regard to the commenter's request to revise the POS codes for HCPCS code G0465, changes to allow for services to be paid in facilities other than the hospital outpatient department or ambulatory surgical center are outside the scope of this rule
Cigna's policy cnf_684 (reviewed July 9, 2025, with revisions through April 2026) approves Zepbound for "Weight Loss in an Adult with Overweight or Obesity" for 8 months initially, when all of the following hold: You are 18 or older
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This is a medical condition, so definitely discuss this with a doctor
We applied rigorous methodology, including PSM, and compared tirzepatide with other active anti-obesity medications to ensure balanced and robust comparisons
A study in July 2024 by researchers at Mass Eye and Ear in Boston found that people taking semaglutide for type 2 diabetes or weight loss had a higher risk of developing nonarteritic anterior ischemic optic neuropathy, an eye condition that can cause blindness, than people taking medications other than GLP-1 drugs for diabetes or obesity
