Using an ERE-luciferase mouse, a reporter mouse that allows monitoring of ER transcriptional activity in a spatiotemporal manner, it was demonstrated that estrogen signaling is locally activated in keratinocytes in vitro (with 1 nM E2) and in vivo (with 10 nM E2)
Contribution of Bcl-2, but not Bcl-xL and Bax, to antiapoptotic actions of hepatocyte growth factor in hypoxia-conditioned human endothelial cells
The half-life data doesnt clearly support a specific timing strategy
Mitochondrial dysfunction and signaling in diabetic kidney disease: oxidative stress and beyond
The reduced form of doxorubicin, resulting from AKR1C3 activity, exhibits lower affinity and capacity to bind to DNA (Heibein et al., 2012)
Cost-utility of albiglutide versus insulin lispro, insulin glargine, and sitagliptin for the treatment of type 2 diabetes in the US