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The utility of this stimuli-responsive platform is demonstrated through two complementary in vivo applications: tumor-targeted prodrug activation triggered by the reductive tumor microenvironment in a 4T1 breast cancer model, and repeatable, on-demand local anesthesia controlled by 405 nm light

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Subsequently, animals were placed in open-field boxes to track their locomotor activities for 30 min to confirm the validity of the model

doi: 10.4161/psb.6.6.15147

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