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Mechanistically, 1,25(OH)D facilitates the formation of VDRRXR heterodimers, which are recruited to antioxidant response elements (AREs), inducing Nrf2 and its downstream targetsincluding HO-1, NQO1, and SOD2and thereby enhancing ROS scavenging capacity [190, 191]

Ke, Y., Ong, L

It can help lighten dark spots, uneven skin tone and pigmentation if you use it regularly

Advanced molecular studies reveal that FOXO4-DRI promotes p53 nuclear exclusion and subsequent mitochondrial targeting, where p53 interacts with BCL-2 family proteins to promote mitochondrial outer membrane permeabilization and cytochrome c release

It also enhances metabolic efficiency, resulting in higher energy levels and improved stamina