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Many peptide-focused clinics don't offer it, while others question its long-term safety profile
Several possible reasons for the lack of efficacy of antioxidants in clinical trials include (i) insufficient antioxidant levels in the target organ, especially in the nervous system, because an integrated bloodbrain barrier (BBB) is a major obstacle to delivering desired substances, including antioxidants, into the CNS
Finally, the modulation of Nrf2 downstream signaling may be considered as a promising strategy for enhancing the astrocytic production of GSH [108], which may counteract the oxidative imbalance that likely affects neurons in neurodegenerative processes such as PD
Inhibition of cellular autophagy in proximal tubular cells of the kidney in streptozotocin-diabetic and uninephrectomized rats
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