Short Half-Life Native GLP-1 has a very short half-life (12 minutes) due to rapid degradation by dipeptidyl peptidase-4 (DPP-4) enzyme
BPC-157, also known as "Body Protection Compound 157" is a peptide derived from human gastric juices
However, in some patients, particularly those with pre-existing hypotension or taking antihypertensive medications, this could potentially contribute to orthostatic symptoms
Easy to Use Directions On an empty stomach: Empty packet in glass or jar (do this first for best mixing)** Add cool or lukewarm water Stir or shake For best results, wait about 20 minutes to eat solid food
Stopping the medication temporarily reduces these compounding risks and allows your body to heal without medication-related complications layered on top of surgical stress
Obes Facts 10(3):160167 [DOI] [PMC free article] [PubMed] [Google Scholar] 42.Mozaffarian D, Agarwal M, Aggarwal M, Alexander L, Apovian CM, Bindlish S et al (2025) Nutritional priorities to support GLP-1 therapy for obesity: A joint advisory from the American college of lifestyle medicine, the American society for Nutrition, the obesity medicine Association, and the obesity society