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A double-blind, placebo-controlled clinical study involved 120 participants who consumed a daily supplement for 90 days based on collagen from hydrolyzed fish, vitamins, L-carnitine, chondroitin sulfate, and glucosamine

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At 14 weeks of age, mice were randomized into treatment groups ( n = 8 per group) receiving subcutaneous injections of PG-102 (15, 30, 60, or 120 nmol/kg), semaglutide (30 nmol/kg), tirzepatide (15 nmol/kg), or vehicle every 3 days for 12 weeks

(1982) assessed decreased GH secretion (0.1 U/kg) 1 year after over 2 weeks of cranial irradiation in the monkeys (Chrousos et al., 1982)