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In patients with T2D, DPP4 inhibitors contribute to glucose homeostasis by decreasing hepatic gluconeogenesis (26, 34)

Authors : S Raeissi, K L Audus Source : The diffusion of delta sleep-inducing peptide (DSIP) across the blood-brain barrier (BBB) has been investigated with an in-vitro model comprised of primary cultures of brain microvessel endothelial cell (BMEC) monolayers

Diabetologia 1995;38:1425-33

A holistic approach to diabetes management, including a healthy diet and regular exercise, is crucial for optimal results

These findings, while promising in laboratory settings, require validation in human studies before clinical applications can be considered

While intended to protect innovation for rare conditions, it could also encourage manufacturers to seek orphan status to avoid negotiation