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While the mechanism by which melatonin and uric acid improved post-thaw sperm viability in the present study remains unknown, the positive effects reported highlight a need for further research, which would benefit from quantifying ROS and oxidative stress simultaneously with sperm parameters to elucidate the biochemical processes causing changes in post-thaw sperm recovery

In good agreement, the association between an OCTN2 SNP (rs27437), down-regulating the OCTN2 expression and the CRC risk has been identified (Zou et al., 2018)

Use only under strict medical supervision

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