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Clinically, high LPLA2 expression correlates with poor patient outcomes, underscoring the ATF4/LPLA2/BMP axis as a pivotal driver of alcohol-accelerated HBV-associated HCC ( Studies in both humans and mice indicate that ALDH2 deficiency leads to greater susceptibility to carcinogen-induced liver tumors

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Fransson L, Dos Santos C, Wolbert P, Sjholm , Rafacho A, Ortster H

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Anyone considering Chelation therapy must consult trained experts and provide proper facilities prior to treatment

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