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Similar to the case of broadly nAb to HIV, the description of rare subset of broadly targeting antibodies is not sufficient to elucidate the mechanism by which we can elicit these antibodies in a wide range of individuals by vaccination

I inject into the front of my thigh or sub cut in my stomach fat, so that's not the problem

As GLP-1 analogs, GLP-1RAs effectively regulate blood glucose by inhibiting glucagon secretion, slowing gastric emptying, enhancing insulin sensitivity, and stimulating insulin secretion [51]

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This can be particularly relevant for drugs with narrow therapeutic windows, such as warfarin (a blood thinner) or digoxin (a heart medication)

Proshkina et al., 2020