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performed a population-based cohort study in Taiwan employing a target trial emulation design to reduce confounding in 97,628 patients with type 2 diabetes [57]
Despite no evidence of this same effect in humans, GLP-1s aren't recommended for people with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome 2 (MEN 2)
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A medically guided plan can help patients lose weight without pushing the body into unnecessary depletion
The next generation of regimens may involve combining GLP-1 or dual GIP/GLP-1 receptor agonists with other nutrient-based hormone receptor agonists or antagonists that offer equal or greater effectiveness with fewer gastrointestinal adverse effects
doi: 10.1111/dom.13847 17 GutzwillerJ
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