As more plans accept obesity as a medical condition, insurance coverage for Zepbound grows
Results from a post hoc subgroup analysis of the SURMOUNT-1 study (NCT04184622), published this year [87] , demonstrated that among 32 pathogenic MC4R variant carriers (1.4% of the study population) with a median age of 41.06 years and a BMI 40 kg/m 2 , treatment with tirzepatide for 72 weeks resulted in an 18.3% reduction in body weight from baseline
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The medicines can cause unwanted gastrointestinal side effects, such as nausea, vomiting, and diarrhea, which might make someone less interested in drinking
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Similar findings were seen with once-weekly, subcutaneous tirzepatide (5 mg, 10 mg, or 15 mg) [27], demonstrating the utility of GLP-1RAs for obesity management