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The active site of the enzyme that binds glycine to the dipeptide -L-glutamyl-L-cysteine is highly specific (57)

This increases the reabsorption burden of the renal tubules, resulting in impaired excretion of renal metabolic waste and contributing to the increase in BUN

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[DOI] [PMC free article] [PubMed] [Google Scholar] 59.Janssen B.G., Byun H.M., Cox B., Gyselaers W., Izzi B., Baccarelli A.A., Nawrot T.S

Application For quantitative determination of reduced glutathione (GSH) and evaluation of drug effects on glutathione metabolism

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