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Description

This data is consistent with the N-terminal residues of GLP-1 and EX4 not being required for the receptor activation when the peptide is fused to the receptor

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Understanding the alternatives provides context for whether semaglutide specifically is the right GLP-1 agonist for you

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N Engl J Med (2023) 389(12):106984

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Mingrone G, Panunzi S, De Gaetano A et al (2015) Bariatric-metabolic surgery versus conventional medical treatment in obese patients with type 2 diabetes: 5 year follow-up of an open-label, single-centre, randomised controlled trial

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