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The review documented GSHs broad roles including antioxidant defence, nutrient metabolism, gene expression, DNA and protein synthesis, cell proliferation and apoptosis, signal transduction, cytokine production, immune response, and protein glutathionylation

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Following AAV-shRNA delivery, mice were fed a MASH-inducing diet rich in fat, cholesterol and fructose, which better recapitulates human liver inflammatory pathology 34 (Fig

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