In rats, the highest dose was approximately 131times (males) and 186times (females) the clinical dose of 10 mg per day, based on AUC exposure
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Your Wellness Goals Berberine has been studied for its effects on glucose regulation, insulin sensitivity, inflammation, and more, which may be relevant for people whove experienced metabolic syndrome, insulin resistance, prediabetes, type 2 diabetes, PMOS, and more
"Effects of doxorubicin-containing chemotherapy and a combination with L-carnitine on oxidative metabolism in patients with non-Hodgkin lymphoma." J Cancer Res Clin Oncol 132(2): 121-128