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Initially anti-inflammatory medications, oral steroids and muscle relaxants may help to reduce the discomfort felt and enable better range of movement

doi: 10.1017/S0033291720003657

Furthermore, those patients exhibited heightened indicators of O&NS, including elevated lipid peroxidation and aldehyde production [172]

For example, curcumin has been evaluated in Phase II clinical studies in pancreatic cancer and colorectal cancer patients, where oral doses up to 8 g/day demonstrated acceptable safety but limited systemic exposure, highlighting pharmacokinetic challenges

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J Endod