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And, without regulatory approval, their safety profile is unknown

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If the findings cannot be replicated, the picture changes

In September, Pfizer offered to buy Metsera for $4.9 billion, but less than a month later, Novo Nordisk made an unsolicited bid of $6.0 billion in cash

Overall, GLP-1 RAs appear to be more efficacious than DPP4 inhibitors in people with type 2 diabetes in terms of improving glycaemic control and reducing body weight ( Yet another aspect to consider is the recurring theme of precision medicine

There have been isolated case reports of liver injury with berberine use