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Retatrutide represents the current frontier in incretin pharmacology a single 39-amino-acid synthetic peptide that simultaneously activates three metabolic receptors: GIP (glucose-dependent insulinotropic polypeptide), GLP-1 (glucagon-like peptide-1), and glucagon

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An article in the January Journal of Drugs in Dermatology looked at reported cutaneous adverse events from popular GLP-1s