The most reported adverse events were gastrointestinal (nausea, vomiting, diarrhea, and constipation)
It is unknown whether RYBELSUS causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans as human relevance of semaglutide-induced rodent thyroid C-cell tumors has not been determined [see Warnings and Precautions (5.1), Nonclinical Toxicology (13.1)]
Remain upright for at least two hours after eating
GLP-1 receptor agonists (semaglutide and liraglutide) and tirzepatide carry a boxed warning about thyroid C-cell tumors in rodents and are contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)
Dehydration & Gastric Slowing Because Wegovy slows your digestion, your body requires more water to process food
The US market is big but complex Novo Nordisk holds patents on semaglutide in the US until 2032