The mean age of onset is approximately 34 years, and prevalence increases with increasing age [24]
Lonapegsomatropin: A Recent Pediatric Approval The FDA approved lonapegsomatropin (TransCon hGH, Ascendis Pharma) in 2021 for pediatric GH deficiency, providing once-weekly dosing [14]
In SLE, dysregulated autophagy contributes to immune hyperactivation, defective apoptotic cell clearance, and increased autoantigen availability
Abell TL, Camilleri M, Donohoe K, et al
Injectable vials are typically used subcutaneously or intramuscularly, and proper sterile technique should be followed to ensure safety and minimize the risk of infection
Others worried about the potential long-term risks of GLP-1s, which could require lifelong use given that weight usually returns when treatment ends