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c-Jun in Schwann cells promotes axonal regeneration and motoneuron survival via paracrine signaling

This actions gives it a high detoxifying power of harmful endogenous substances

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Its activity in fermentative cells is fairly modest and can be increased by respiration, starvation, or ethanol exposure (Bagamery et al., 2020)

Women using oral contraceptives should use a non-oral method or add a backup method for 4 weeks after initiating tirzepatide and for 4 weeks after each dose increase due to potential reduced contraceptive effectiveness

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