One obvious advantage of the small molecule agonists in the replacement of peptide GLP-1 analogues is that they could be administered orally, thus avoiding the discomfort of subcutaneous injections and increasing the compliance of patients
A simpler workflow with less exposure to bottlenecks: Fewer impurities mean fewer byproducts to wash out, which cuts down on cycle time and potentially clears the way for less intensive downstream purificationall while improving overall yield
Maria feels her hopeful attitude and compassionate care team at Wellstar helped her come through treatment with positive outcomes
Disclosures: Saleha Aziz: Nothing to Disclose, Arsalan Hamid: Nothing to Disclose, Michael Hall: Nothing to Disclose, Mark Pedersen: Nothing to Disclose, Jan Petrasek: Nothing to Disclose 2037 HEPATIC STELLATE CELL-DERIVED THBS2 PROMOTE INTRAHEPATIC INFLAMMATORY INFILTRATION BY REGULATING SPP1 SECRETION DURING LIVER FIBROGENESIS Hong Li 1 Ning Zhang 2 Wen Zhang 1 Wenyue Wu 1 Yameng Sun 1 Shuyan Chen 1 Qi Han 1 Xuzhen Yan 3 Aiting Yang 1 Hong You 1 Wei Chen 1 , 1 Beijing Friendship Hospital,Capital Medical University, 2 Beijing Friendship Hospital, Capital Medical University, 3 Beijing Friendship Hospital, Capital Mdeical University Background: Our previous study demonstrated that Thrombospondin-2 (THBS2) plays a critical role in hepatic stellate cells (HSCs) activation and the progression of liver fibrosis through TLR4-FAK/TGF- signaling
No other studies have replicated those findings
Long-term safety is under study
