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Pharmacological inhibition of glycolysis diminishes H3K9la and angiogenesis, representing a novel therapeutic method for pathological neovascularization

Synergistic combinations with immunotherapy, radiotherapy or ferroptosis-inducing agents also hold strong potential

10.3389/fimmu.2024.1387903 182 ProfumoE.ButtariB.SasoL.RiganoR

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76 In a cell experiment, when renal tubular cells experienced hypoxia and then reoxygenation, the levels of HIF-1 and BNIP3 were increased, mediating mitophagy, which could protect cells from cell apoptosis

References: FDA Orange Book