tirzepatide updates vs topiramate in Medicine Mounjaro (Tirzepatide) Prescribing Update –

Each change can affect bowel rhythm

Within both the LRx Germany and LRx UK, data collected include year of birth (Germany) or age group (UK), gender, geographic information in addition to information on co-prescribing and new, switch, and repeat dispensations

The tirzepatide drugs, such as Mounjaro and Zepbound, target the GLP-1 pathway along with a second one, the GIP pathway

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Toki et al., 2021)

The appetite suppression these drugs create makes it difficult to eat enough protein to preserve muscle mass, and roughly 25% of weight lost on GLP-1 drugs comes from lean tissue on average, with some trials reporting up to 40%